May 2013

Analysis of combined anti-tuberculous drug induced neurotoxicity in the cerebral cortex of adult Wistar rats by immunohistochemistry

Combined Isoniazid (INH) and Rifampicin administration still remain as two of the main drugs of choice in the treatment regimes of tuberculosis (TB) world wide, particularly in Africa, where tuberculosis incidence rates are among the highest in the world. This study evaluated the effects of chronic administration of combined Isoniazid/Rifampicin on the cerebral cortex of the adult rats by immunohistochemistry....

Author(s): Fakoya Francis Adelade, Osoniyi Omolaja and Obuotor Efere Martins

May 2013

Behavioural and haematological studies on effects of lycopene in Wistar rats subjected to psychological stress

This study investigated the effects of prior lycopene supplementation on behaviour and haematology of Wistar rats subjected to psychological stress. Four groups of Wistar rats, each comprising seven animals were investigated: unstressed (U-Control), unstressed + lycopene (U+Lyco), stressed (SControl) and stressed + lycopene (S+Lyco). Olive oil was given by oral gavage to each rat in the groups, either singly or mixed...

Author(s): Ogundeji, T., Ayo J. O., Aluwong T. and Mohammed A.