October 2011

Sex differential effects of acute caffeine administration on open field novelty induced behaviour in Swiss albino mice

The study investigated the effects of acute systemic administration of caffeine on novelty induced behaviours in male and female albino mice. The aim was to assess the effects of gender (if any) on the neurobehavioural response to a single intraperitoneal (i.p.) injection of caffeine. Eighty Swiss albino mice (aged 6-8 weeks, mean weight, 22.5 ± 2.5 g) were divided into four treatment groups (n =20)....

Author(s): Onaolapo, Olakunle James and Onaolapo, Adejoke Yetunde

October 2011

Effects of methamphetamine on the hippocampus of rats: Behavioural and morphological approach

This investigation examined the effects of methamphetamine (METH) on performance of rats using the Morris water maze and on the morphology of the hippocampus. Twelve adult Wistar rats were used for this study. Animals were randomly assigned into two groups (A and B) of six each. Group A rats served as control and were given normal saline. Group B animals were given single administration of METH (10 mg/kg, i.p.). ...

Author(s): Ijomone Omamuyovwi M., Nwoha Polycarp U., Olaibi Olayemi K., Obi Augustine U. and Alese Magaret O.