Journal of
Physiology and Pathophysiology

  • Abbreviation: J. Physiol. Pathophysiol.
  • Language: English
  • ISSN: 2141-260X
  • DOI: 10.5897/JPAP
  • Start Year: 2010
  • Published Articles: 49

Table of Content: December 2013; 4(5)

December 2013

Neurotoxicity of arsenite (As III): In vitro electrophysiological approach to studying neural activity in rat brain slices

Arsenite (Arsenic III) is ubiquitous and a widely distributed environmental toxin implicated in the aetiology of several neurological disorders. It is found in sea food, chemicals and pesticides. As(III) is also a mitochondria poison that induces reactive oxygen species (ROS) formation and membrane distortion. This study is aimed at proposing an in vitro method to detecting neural activity in rat’s brain treated...

Author(s): Ajonijebu Duyilemi Chris, Ogundele Olalekan Michael, Omoaghe Adams Olalekan, Fabiyi Temitope Deborah and Ojo Abiodun Ayodele

December 2013

Cardio protective effects of Nigella sativa oil on lead induced cardio toxicity: Anti inflammatory and antioxidant mechanism

The present study aimed to evaluate cardio-protective effect of Nigella sativa oil (NSO) on lead induced cardio toxicity. Forty five albino adult rats were randomly divided into 3 groups: control lead (Pb) group that received lead acetate (20 mg/kg/day) 3 times weekly for 8 weeks and PB + NSO group (rats pretreated with Nigella sativa oil (4 ml/kg) orally for 1 h before administration of lead acetate (given as in Pb...

Author(s): Marwa A. Ahmed and Khaled M. A. Hassanein