December 2013
Neurotoxicity of arsenite (As III): In vitro electrophysiological approach to studying neural activity in rat brain slices
Arsenite (Arsenic III) is ubiquitous and a widely distributed environmental toxin implicated in the aetiology of several neurological disorders. It is found in sea food, chemicals and pesticides. As(III) is also a mitochondria poison that induces reactive oxygen species (ROS) formation and membrane distortion. This study is aimed at proposing an in vitro method to detecting neural activity in rat’s brain treated...
December 2013
Cardio protective effects of Nigella sativa oil on lead induced cardio toxicity: Anti inflammatory and antioxidant mechanism
The present study aimed to evaluate cardio-protective effect of Nigella sativa oil (NSO) on lead induced cardio toxicity. Forty five albino adult rats were randomly divided into 3 groups: control lead (Pb) group that received lead acetate (20 mg/kg/day) 3 times weekly for 8 weeks and PB + NSO group (rats pretreated with Nigella sativa oil (4 ml/kg) orally for 1 h before administration of lead acetate (given as in Pb...