March 2023
Contribution of high fat diet to the development of gestational diabetes mellitus in rats
Gestational diabetes mellitus (GDM) is a glucose intolerance resulting in hyperglycemia with onset or first recognition during pregnancy. High fat diet (HFD) is one of the contributing factors to GDM. This study evaluated the contribution of HFD in differential adipose tissue (AT) expansion and subsequent development of GDM in Wistar rats. Pregnant and non-pregnant rats were given streptozotocin (STZ) by a single...