April 2016

Influence of infective stage (L3) dose on the outcome of microfilaremia, peripheral white blood cells and humoral immune response in Loa loa experimentally infected Mandrillus sphinx

Analyses were performed to assess how the dose and frequency of administration of the natural infective stage (L3) affects events in the peripheral blood of an infected host. A blood sample was collected from different mandrills (Mandrillus sphinx) infected once with 1000 L3 Loa loa, 250 L3 four times, 100 L3 once and 25 L3 four times. Enzyme-linked immunosorbent assay (ELISA) was used to measure levels of...

Author(s): J. P. Akue, P. Makouloutou,  R. M. Moutsimbi, H. Moukana and E. Leroy