December 2014

Development and evaluation of lateral flow test for the detection of trypanosomes in tsetse flies

Lateral flow test (LFT) which is based on antibodies raised against the Trypanosoma brucei peptide was evaluated for its analytical sensitivity, specificity, positive predictive value and negative predictive values in order to assess its utility for surveillance of trypanosome infections in tsetse flies. The diagnostic test agreement of the FLT and microscopy was 91.0% and kappa value of 80.5% at the confidence interval...

Author(s): Enyaru C. K. John, Njuguna James, Alibu Vincent Pius, Matovu Enock, Malele I. Imna, Chisi E. John, Mbongo Nicolas, Mansinsa Philemon, Intisar E. l. Rayah, Mohammed Yassir, Mubarak Mustafa, Ochi Erneo and Nantulya Vinand  

December 2014

Viability loss and ultrastructural changes on protoscolices of human hydatid cysts induced by retinoic acid

Surgical removal of intact hydatid cyst is the most effective treatment for hydatid disease. Recurrence of hydatid cyst is mainly due to dissemination of protoscolices (PSCs) rich fluid during the surgical operation. Therefore, preoperative instillation of a scolicidal agent into the cyst is a common practice with adverse side effects of the used drugs. All-trans retinoic acid (atRA) is the physiological mediator of...

Author(s): Doaa Abdelhafeez Yones, Enas Abdelhameed Mahmoud, Ragaa Ali Othman, Mohamed Korany and Tarek Hassan El-Metwally