Research in Pharmaceutical Biotechnology

  • Abbreviation: Res. Pharm. Biotech.
  • Language: English
  • ISSN: 2141-2324
  • DOI: 10.5897/RPB
  • Start Year: 2009
  • Published Articles: 42

Table of Content: March 2012; 4(1)

March 2012

Evaluation of Sesamum indicum gum as a binder in the formulation of paracetamol granules and tablets

  Comparative evaluation of Sesamum indicum gum as a binder in the formulation of paracetamol (PCM) granules and tablets was performed using acacia, gelatin, and Sodium carboxyl methylcellulose (SCMC) as standard binders for comparison. The properties of granules and tablets such as; flow rate, angle of repose, density, weight uniformity, crushing strength, friability, disintegration rate and release...

Author(s): Clement Jackson⊃, Ekaette Akpabio⊃, Romanus Umoh⊃, Musiliu Adedokun⊃, ⊃Peace Ubulom and Godwin Ekpe⊃

March 2012

Rosiglitazone protection against experimentally-induced intestinal ischemia/re-perfusion

  Several studies have shown that peroxisome proliferator-activated receptor-g (PPARg) agonists protect against ischemia/re-perfusion (I/R) damage in different organs. This study was carried out to assess the possible role of PPARg on intestinal I/R-mediated tissue injury. This was achieved by evaluating the effects of the PPARg agonist rosiglitazone and the PPARg antagonist bisphenol A...

Author(s):   Wageh M. Awara, Alaa E. El-Sisi, Sally E. Abu Risha, Karima I. El-Desouky and Sherief A. Mostafa