July 2018

Prevalence of glucose-6-phosphate dehydrogenase (G6PD) deficiency (A-376/202) in homozygous sickle cell patients in Senegal and its clinical impact

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common worldwide enzymopathy with approximately 400 million individuals affected. This inherited disease is sex-linked recessive inheritance. The high prevalence of certain variants of G6PD in different populations and ethnic groups increases the likelihood of finding associations with other pathologies. Sickle cell disease and thalassemia are the most...

Author(s): Dominique Doupa, Ousseynou Boye, Maguette Ndiaye, Mamadou Djité, Pape Matar Kandji, Sidy Mohamed Seck, Demba Makalou, Aminata Lam, Marie Pierre Diouf, Arame Ndiaye, Blaise Felix Faye, Souleymane Thiam, Abdourahmane Samba, Fatou Diallo, Papa Madieye Gueye, Alassane Diatta, Babacar Faye, Ibrahima Diagne and Saliou Diop