October 2012

Effects of methanol extract of Vernonia amygdalina leaf on survival and some biochemical parameters in acute Trypanosoma brucei brucei infection

The effects of methanol extract of Vernonia amygdalina leaf (chosen from several extracts tested) on survival, parasitaemia, packed cell volume and some biochemical parameters were investigated in acute Trypanosoma brucei brucei infection. Results showed that the extract was relatively safe with median lethal dose, LD50 ≥5000 mg/kg/day. Although none of the extracts tested cured infected...

Author(s): Yusuf, Aminu Bashir, Umar, Ismail Alhaji and Nok, Andrew Jonathan

October 2012

Measurement of cholesterol sub-fractions, high density lipoprotein 2 and high density lipoprotein 3, in HIV infected patients treated with highly active antiretroviral therapy in Burkina Faso

This paper described dyslipidemia caused by the metabolic effects of HIV and exposure to antiretroviral therapy. The aim of this study was to appreciate the interest of the measurement of HDL sub-fractions in the monitoring of human immunodeficiency virus (HIV) infected patients on antiretroviral treatment. A case-control study was carried out on 31 HIV infected before (naive) highly active antiviral therapy (HAART...

Author(s): Jean Sakandé, Josiane B Kaboré, Elie Kabré, Boblwendé Sakandé and Mamadou Sawadogo