April 2011
Chemical composition and biological activity of the volatile oils of Hyptis spicigera against Trypanosoma brucei brucei, (Tbb) found in Northern Nigeria
The hydrodistillation of the fresh leaves of Hyptis spicigera gave a colourless volatile oil with yield of 0.65%.The volatile oil gave forty compounds on the basis of gas chromatography-mass spectroscopy (GC-MS) with low composition of cineole(4.11%) and caryophyllene (2.61%) while α-pinene (12.16%) β-pinene(9.47%) and α-phellandrene (10.19%) were predominant compounds. The...
April 2011
Synthesis, characterization and trypanocidal activity of some aromatic thiosemicarbazones and their 1,3,4-thiadiazolines derivatives
The thiosemicarbazones of six aromatic ketones were synthesized as well as their 1,3,4-thiadiazolines derivatives obtained by cyclization under acetylating condition with yields going from 40 to 90%. The products purity was confirmed by mass spectrometry coupled with high-performance liquid chromatography (LC/MS) and there were characterized using spectrometry IR, NMR 1H and 13C (nuclear magnetic...
April 2011
Preliminary phytochemical and antimicrobial screening of the leaf extract of Cassia singueana Del
Ethanolic and aqueous extracts of Cassia singueana Del. leaves were screened for their antimicrobial activity against Staphylococcus aureus, Streptococcus pyogen,Escherichia coli, Salmonella typii and Shigella dysentery. The result indicated that the extracts inhibited the growth of one or more test pathogens. The ethanolic extract showed a broad spectrum of...
April 2011
Multiple regression analyses of kinetics of aquation reactions of some chromium (III) – alkyl amine complexes in mixed solvent media- A study of solvation mechanics
Molecular dynamics of the aquation reactions of the complexes [Cr(en)2Cl2]Cl,[Cr(tn)2Cl2]Cl,[Cr(tetren)Cl]Cl2, [Cr(pn)2Cl2]Cl, [Cr(trien)Cl2]Cl and [Cr(dien)Cl3] have been extensively studied in mixed solvent media. Kinetics and thermodynamic parameters have been evaluated and the results are interpreted carefully in the light of statistical and regression models. Key words: Cr (III) complexes,...
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