November 2012
Hepatoprotective and antioxidant activity of Spilanthes paniculata flower extracts on liver damage induced by paracetamol in rats
The present study was undertaken to investigate the antioxidant and hepatoprotective effect of Spilanthes paniculata Wall. ex DC flower extracts against paracetamol-induced liver damage. The study was conducted in 36 male Wistar rats of either sex, and six groups were established. While the first group was maintained as normal control (NC, distilled water), Groups 2 to 6 were administered 3 g/kg Paracetamol...
November 2012
Chemical composition, antibacterial and antioxidant activities of a new essential oil chemotype of Algerian Artemisia arborescens L.
The aim of the present study is to investigate the chemical composition, antibacterial and antioxidant activities of three essential oils extracted by hydrodistillation from the aerial parts ofArtemisia arborescens L., which was collected from three different regions near Tlemcen city in the West Northern of Algeria: Beni Snous, Bidar and Chetouane. The chemical composition was investigated using both capillary gas...
November 2012
An optimal establishment of an acute hyperglycemia zebrafish model
Recently, zebrafish has shown the potential to become an important in vivo model for diabetes-related research. In this study, we performed a validation study for the establishment of optimal hyperglycemia involving the following factors: alloxan concentrations of 100, 200, 300, and 400 mg/100 ml; exposure times of 30, 60, 120, and 180 min to an alloxan solution and water glucose solution; and water glucose...
November 2012
Complex system entropy method of Professor Kong Guangyi’s experience in the treatment of menstrual disease
This study used data mining technology to study Professor Kong Guangyi’s medication experience for the treatment of menstrual period. 612 treatments of the medical records of the menstrual period of the patients of Professor Kong Guangyi were collected and data mining technology was used to study his prescribed drug. For single herb, frequency statistical method was used; in association between paired...
November 2012
Biological screening of ethyl acetate extract of Hedera nepalensis stem
Hedera nepalensis is commonly used in folk medicines for the treatment of cough and other human ailments; therefore it was selected for phytochemical and antimicrobial screening. Its phytochemical screening showed the presence of different classes of secondary metabolites. The ethyl acetate extract of its stem showed the presence of steroids, terpenoids, saponins and flavonoids. Terpenoids and flavonoids were...
November 2012
Appropriateness of digoxin level monitoring in a children's hospital
To evaluate the proportion of inappropriate digoxin level determinations in children at Children’s Hospital of Fudan University. A retrospective analysis of 291 digoxin level determinations in 210 inpatients was performed. Appropriateness criteria were based on existing criteria that were revised using local expert opinion. The main outcome measure was the proportion of digoxin levels assessed as inappropriate by...
November 2012
Relationship among C-reactive protein, iron status, oxidative stress, and pulmonary tuberculosis
This study aims to assess the effects of acute tuberculosis and drug treatment on oxidative stress markers [malondialdehyde (MDA) and total antioxidant status (TAS)], C-reactive protein (CRP), and body iron index. A total of 20 patients with active tuberculosis (treatment group) and 50 healthy subjects (control group) were selected. MDA, TAS, serum CRP, serum iron, serum total iron binding capacity, transferrin...
November 2012
Potential drug targets prediction for H1N1 influenza A based on protein-protein interaction networks
In this paper, some proteins were determined as potential drug targets for H1N1 influenza A. These proteins were found using three steps: i) determining a set of human proteins that had interactions with the proteins of H1N1 virus, and assigning a weight to each protein; ii) mapping the set of human proteins into the human protein-protein interaction networks; iii) combining the topological properties of the network and...
November 2012
Prediction of polymorphisms in DNA repair genes on the prognosis of bone tumors with methotrexate, intravenous adriamycin and intra-arterial cisplatin chemotherapy
We investigate the relationship of SNPs in XRCC1, ERCC1 and ERCC2 to methotrexate intravenous adriamycin and intra-arterial cisplatin chemotherapy response and survival in bone cancer patients. 281 consecutive patients diagnosed with bone tumor between January 2003 to January 2005, and they were followed up until the end of January 2010. Polymorphisms in XRCC1Arg280His, XRCC1Arg399Gln, ERCC1 Asn118Asn, ERCC1 Gln504Lys,...
November 2012
Association study between the human resource of pharmacy and SCI dissertation
With the development of scientific researches in China, more and more domestic researchers have their research results published in overseas journals, especially those that are indexed by Science Citation Index. There are great progresses in the field of Traditional ChineseMedicine, and many research results are published in the journals indexed by Science Citation Index. Hence, the Science Citation Indexed...
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