July 2014

Biochemical alterations induced by phytotherapic tincture with antiophidic activity in male Wistar rats

For more 30 years, phytotherapic tincture Específico-Pessôa has been used as supportive therapy in envenoming by snakebites in Brazilian folk medicine. However, little or no information is available in the literature about the safety/toxicity of this phytotherapic tincture. The present work was designed to investigate the effect of this tincture by maximum dose (0.75 ml kg-1 body weight) on acetyl- and...

Author(s): Alana Meira Reichert, Carla Brugin Marek, Ana Maria Itinose, Renata Prestes Antonangelo, Cristiane Weirich Lenzi, Rodrigo Suzuki and Paulino Yassuda Filho

July 2014

Biocompatibility research of a novel biodegradable ion exchange resin

The in vivo pharmacological and toxicological investigation of biodegradable ion exchange resin was carried out to provide evidence for further clinical utilizations. Acute toxicity study, general pharmacological studies, hemolytic experiments, systemic hypersensitivity experiments and vascular stimulation experiments were conducted. The general pharmacological effects of the biodegradable ion exchange resin on the...

Author(s): Hongfei Liu, Weisan Pan, Changshan Sun, Xiaomian Zou, Min Fu, Shuang Shuang Shi and Hui Ding