June 2010

Theileria parva apical membrane antigen-1 (AMA-1) shares conserved sequences with apicomplexan homologs

The apical membrane antigen-1 (AMA-1) is a leading malaria vaccine candidate that is expressed in mature stage parasites and is thought to be essential for invasion. In Plasmodium falciparum, AMA-1 is localized initially to the micronemes, apical organelles of the parasite. A similar apicomplexan parasite, Theileria parva infects and transforms lymphocytes of cattle and African buffalo causing the disease called East...

Author(s): Nyerhovwo J. Tonukari

June 2010

Urinary schistosomiasis: Efficacy of praziquantel and association of the ABO blood grouping in disease epidemiology

Schistosomiasis, one of the neglected tropical diseases continues to plague communities with little or no access to potable water and with high water contact activities. Ipogun village in Ondo State is one of such communities in Nigeria. This study assessed the efficacy of praziquantel and the association of the ABO blood grouping in disease epidemiology in the only private primary school in the village. Ten milliliters...

Author(s): M. O. Oniya and O. Jeje