March 2010

Unusual location of BCR/ABL fusion gene in four CML patients with masked Philadelphia chromosome

The author describes atypical BCR/ABL fusion patterns among CML patients using FISH technique. The fusion BCR/ABL gene is usually observed at the der(22) chromosome while atypical rearrangements in CML patients are rare. As the relocation of BCR/ABL1 fusion sequence on sites other than 22q11 represents a rare type of variant Ph-translocation, the present study may highlight the hot spots involved in CML pathogenesis and...

Author(s): M. Brahmbhatt  Manisha, S. Patel Prabhudas, J. Trivedi Pina, P. Patel Beena, B. Gajjar Sarju, N. Dalal Esha, M. Patel Dharmesh, S. Purani Sejal,  N. Shukla Shilin, M. Shah Pankaj and R. Bakshi Sonal

March 2010

A ten year retrospective study of incidence of cleft lip and/or palate in babies born in the CISAM maternity unit, Recife, Brazil

An epidemiologic study of children’s prevalence born with cleft lip and/or palate in the Amaury de Medeiros Integrated Health Center (CISAM) maternity unit, between January 1998 and December 2008. Variables instructed are prematurity, APGAR index, type of cleft, other associated anomalies besides clefts, mother’s age, occurrence of infection in mother and use of drugs during pregnancy. Descriptive analysis...

Author(s): Ana Paula Veras Sobral, Édila Figuerêdo Feitosa, Fabiane Ferraz Lima and Marina de Almendra Freitas Leitão

March 2010

Histopathologically documented gastrointestinal cytomegalovirus infection in immunosuppressed patients: Clinicopathologic analysis with serum quantitative PCR correlation

Cytomegalovirus (CMV) infection of the gastrointestinal (GI) tract is associated with high mortality in immunosuppressed patients. Few studies have correlated serum viral load with histopathological findings in this setting. Gastrointestinal biopsies from 28 immunosuppressed patients showing CMV cytopathic effect were studied by immunohistochemistry (IHC) and in situ hybridization (ISH). Quantitative...

Author(s): Roger Klein Moreira, Christine Norton, Flavia Nunes Rosado, Cynthia Cohen and Frederick Nolte

March 2010

Ethnobotanical uses of medicinal plants of two ethnoecological regions of Cameroon

This paper documents the herbal drugs that are used in two ethnoecological regions of Cameroon, namely littoral and South-west and Sudano-sahelian regions. The data on popular medicinal plants used to cure several diseases were collected through direct interviews with herbalists, traditional healers and customers between 2006 and 2007. An inventory of 289 plants species belonging to 89 families was prepared along with...

Author(s): T. Jiofack, C. Fokunang, N. Guedje, V. Kemeuze, E. Fongnzossie, B. A. Nkongmeneck, P. M. Mapongmetsem and N. Tsabang

March 2010

Resistance to respiratory illness and antibody response in open water swimmers during training and long distance swims

The immune response in open water swimmers during training and long-distance swims (LDS) as well as their resistance to respiratory illnesses has not been investigated. The immune, metabolic and hematological response was determined in experimental  and control groups of swimmers (7 and 8 athletes, respectively) during 6 months of training, as well as in the experimental group during each one of three LDS (>6 h)...

Author(s): Alexander Kormanovski, Francisco Castañeda Ibarra, Eleazar Lara Padilla and Rafael Campos Rodriguez

March 2010

Management of childhood diarrhea by patent medicine vendors in Enugu North Local Government Area, South-east Nigeria

The study was a descriptive cross-sectional study carried out in Enugu North LGA, Enugu state, Nigeria in November, 2008. Ninety patent medicine vendors were studied using semi-structured interviewer administered questionnaires. Information on knowledge and management of diarrhea in under-fives was obtained. The patent medicine vendors had good knowledge (64.0%) of the types, causes, signs and effects of diarrhea but...

Author(s): Emmanuel Nwabueze Aguwa, Patricia Nonye Aniebue and Ikechukwu Emmanuel Obi

March 2010

Antibacterial potential of chosen mangrove plants against isolated urinary tract infectious bacterial pathogens

Five Indian mangrove plants (Rhizophora apiculata, Rhizophora mucronata, Bruguiera cylindrica, Ceriops decandra, Avicennia marina) /parts (hypocotyls, bark, collar and flower) were investigated to evaluate the antibacterial activity against UTIs bacterial pathogens. Sixty nine bacterial strains were isolated from mid urine samples of 75 males and 75 females from Thondi coastal area, Ramanathapuram and were identified by...

Author(s): S. Ravikumar, M. Gnanadesigan, P. Suganthi and A. Ramalakshmi   

December 2010

Evaluation of bio-safety and antioxidant activity of the fruit and leaf of Saba florida (Benth.) from Ibaji forest

This study aimed to determine the activity of Saba florida extracts against brine shrimps (Artemia salina) and to investigate in vitro antioxidant activity of the extracts as well. Extracts of the fruit pulp, fruit pericarp and leaf of the plant were subjected to bioscreening study to detect cytotoxic activity by the brine shrimp lethality bioassay. The results obtained showed that the crude alcohol...

Author(s): Omale James and B. Omajali Jacob