October 2011
Intragenotypic diversity in the VP4 encoding genes of rotavirus strains circulating in adolescent and adult cases of acute gastroenteritis in Pune, Western India: 1993 to 1996 and 2004 to 2007
Genetic variability of rotaviruses circulating in Pune, India at the two time points was determined by characterizing VP4 genes in 131 rotavirus strains detected in adolescent and adult cases of acute gastroenteritis. The multiplex RT-PCR classified the VP4 genes in 73 P[4] (43.2%), 69P[8] (40.8%) and 27 P[6] (16.0%) genotypes. Sequencing and phylogenetic analysis revealed increase in the...
October 2011
No xenotropic murine leukemia virus-related virus (XMRV) detected in Swedish monozygotic twins discordant for chronic fatigue
The recent debate regarding the possible involvement of xenotropic murine leukemia virus-related virus (XMRV) in chronic fatigue syndrome (CFS) in humans has been intense due to the conflicting results from different studies and the unclear origin of the XMRV virus. In this study, we have addressed this issue by screening 47 pairs of monozygotic twins discordant for CFS using a sensitive PCR...