November 2017

Phytochemical composition, acute toxicity and phytohormonal activity of hydroalcoholic extract of Pentadesma butyracea (Clusiaceae Sabine (1824)) seeds

Pentadesma butyracea is a rainforest species of Clusiaceae family with multi-values for human healthcare according to previous ethnobotanical survey. In spite of this traditional use of P. butyracea, there is a lack of scientific knowledge of its biological activities. Therefore, the aim of this study was to identify the major phytochemical compounds of P. butyracea hydroalcoholic seeds extract and to assess...

Author(s): TINDANO Basile, BAYALA Balé, DOUKOURE Maya, BELEMTOUGRI G. Raymond, TAMBOURA H. Hamidou and SAWADOGO Laya

November 2017

Anti-proliferative and cytotoxic effects of methanol extract of the leaves of Momordica charantia L. (Cucurbitaceae) on vascular smooth muscle cells (VSMC) and HT-29 cell lines

Momordica charantia has been used traditionally for the treatment of several ailments. Some natural plant products are known to exhibit cytotoxic or anti-proliferative effects on cancer cell lines, such plants offer a promising therapeutic approach as an anti-tumor agent. In this study, the anti-proliferative effects of graded concentrations of methanol leaf extract of M. charantia (MEMC) at different point time was...

Author(s): Ofuegbe S. O., Oyagbemi A. A., Omobowale T. O., Fagbohun O. S., Yakubu M. A. and Adedapo A. A.