April 2022
Antioxidant and antihyperlipidemic activities of unique nicotinyl polysaccharide from the green seaweed Ulva pertusa
Nicotinyl derivative of polysaccharide (NU) from the green seaweed Ulva pertusa (Chlorophyta) has unique structure and strong antioxidant activity in vitro. In the present study, in vivo antioxidant and antihyperlipidemic activities were tested in the livers of hyperlipidemic mice. Activity levels of superoxide dismutase, glutathione peroxidase (GSH-PX), catalase, and malondialdehyde were observed. At the 500 mg/kg...
April 2022
Herbal medicine development and compliance to regulatory guidelines in Imo State Nigeria
Herbal medicine is an important age-long resource for healthcare. The aim of this study was to determine the development of herbal medicine in relation to compliance to regulatory guidelines and product development in pursuance of the integration of herbal medicine into the healthcare system in Nigeria. Using Imo State as a case study, a cross-sectional investigation was conducted among the Traditional Medicine...
April 2022
Phytochemical analysis and safety evaluation of ethanol roots extract of Erythrina sacleuxii hua in Wistar albino rats
Erythrina sacleuxii, one of five Erythrina species found in Kenya, is a stiffly multi-branched deciduous tree reported to have antiplasmodial, antifungal, anti-bacterial and anti-cancer activities. This study aimed at evaluating acute and sub-acute oral toxicity of E. sacleuxii roots ethanolic extract. Phytochemical analysis was conducted on Fourier transform infrared spectroscopy and Gas Chromatography-Mass...
April 2022
In vitro antiproliferative potential of crude extracts from Carica papaya L. (Caricaceae) black seeds against prostate cancer cell lines'
Black seeds from papaya plants are utilized as traditional medicine in African and Asian cultures to improve the functioning of the male reproductive system and management of prostate cancer. This study analyzed the phytochemical composition, antiproliferative activity and cytotoxicity of Carica papaya black seeds against the prostate cancer cells and Vero cells. Phytochemical screening was performed by standard...
April 2022
Analgesic, anti-inflammatory and oxytocic activities of Dracaena steudneri Engl. stem bark aqueous extract in Wistar rats
Dracaena steudneri Engl. (Dracaenaceae) is a medicinal plant that is used in labour by traditional birth attendants to induce labour, relieve pain and treat various diseases; albeit no documentation. This study determined the analgesic, anti-inflammatory and oxytocic effects of the D. steudneri stem bark aqueous extract. D. steudneri stem bark was collected, authenticated, oven-dried at 45ºC for 48 h, pulverized...
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