April 2015

Antiprotozoal and cytotoxic activities, and the acute toxicity of extracts from of Brucea sumatrana Roxb. (Simaroubaceae) leaves collected in Mai-Ndombe, Democratic Republic of Congo

Results from the in vitro evaluation of the antiprotozoal activity of the aqueous extract, the 80% methanol extract and its fractions from the leaves of Brucea sumatrana against Trypanosoma brucei brucei, Trypanosoma cruzi, Lesihmania infantum, the multidrug-resistant K1 and chloroquine-sensitive NF54 strains of Plasmodium falciparum indicated that all samples from the leaves extract presented interesting antiprotozoal...

Author(s): Cimanga R. Kanyanga, Tshodi M. Ehata, Nsaka S. Lumpu, Kikweta C. Munduku, Mbenza A. Phuati, Kambu O. Kabangu, Cos, P., Maes, L., Apers, S., Vlietinck, A. J. and Pieters, L.

April 2015

New pentacyclic triterpene ester and flavone glycoside from the biologically active extract of Carduus pycnocephalus L.

Bioassay guided phytochemical investigation of petroleum ether, chloroform and butanol  fractions obtained from biologically active total alcoholic extract of Carduus pycnocephalus led to isolation of  two new compounds, 3-O-acetyl-ursolic acid-28-ethyl ester (compound 1) and diosmetin-7-O-α-L-arabinopyransyl (1```→4``)-β-D- glucopyranoside (compound 5) along with  three  known...

Author(s): Wafaa H. B. Hassan, Hanan M. Al-Youssef, Latifa AL-Shammari and Rehab H. Abdallah

April 2015

Characterization of alkaloid constitution and evaluation of antimicrobial activity of Solanum nigrum using gas chromatography mass spectrometry (GC-MS)

In this study, the alkaloid compounds of Solanum nigrum have been evaluated. The chemical compositions of the leaf methanol extract of S. nigrum were investigated using gas chromatography-mass specroscopy (GC-MS). GC-MS analysis of S. nigrum alkaloid leaf methanol extract revealed the existence of the cyclopentasiloxane-decamethyl, L-proline, ethylester, 2-ethyl-1-butanol, methyl ether, cyclopentasiloxane-ocamethyl,...

Author(s): Huda Jasim, Ameera Omran Hussein, Imad Hadi Hameed and Muhanned Abdulhasan Kareem