March 2010

Anti-diabetic effects of aqueous fruits extract of Diospyros lotus L. on streptozotocin-induced diabetic rats and the possible morphologic changes in the liver, kidney and heart

The aim of this study was to assess hypoglycemic effect of aqueous fruits extract ofDiospyros lotus L. on streptozotocin-induced diabetic rats and the possible morphologic changes in the liver, kidney and heart. Diabetes mellitus was induced by a single intraperitoneal (IP) dose of 70 mg/kg of streptozotocin (STZ). Animals were post-treated with different doses of D. lotus L (500, 750, 1000 and 1500 mg/kg) by...

Author(s): Mohammad Azadbakhta, Shohreh Safapour, Amirhossein Ahmadi, Maryam Ghasemi and Mohammad Shokrzadeh

March 2010

Bioactivity-directed separation of an anxiolytic fraction from Aethusa cynapium L.

The present study has been designed to evaluate the putative anxiolytic activity of petroleum ether, chloroform, methanol and water extracts of the aerial parts ofAethusa cynapium using the widely accepted elevated plus-maze model in mice. An attempt has been made to isolate the bioactive fraction by resorting to bioactivity directed fractionation and chromatographic procedures like column and flash chromatography....

Author(s): Richa Shri, Manjeet Singh and Anupam Sharma