Streptococcus pneumonia and antimicrobial resistance, Hawassa Referral Hospital, South Ethiopia
July 2011
Bacterial resistance to antimicrobial agents is an increasing problem in many areas of the tropics. To assess drug resistance pattern of Streptococcus pneumoniae among clinically diagnosed cases of pneumonia, meningitis and otitis media in Hawassa Referral Hospital, Southern Ethiopia. A cross-sectional survey was conducted on 152 cases from sputum, cerebrospinal-fluid, and ear discharge samples. Blood agar and...
Coinfection of typhoid and malaria
July 2011
Rampant and unnecessary use of iron supplementation to correct possible anemia in malaria and other infections is dangerous, since excess iron may predispose to salmonellosis. Intracellular bacteria, such as Salmonella typhimurium has an obligate requirement for iron to support intracellular growth and survival. Complements have unique role in salmonella co-infection with malaria because complements like C1q...
What is the best approximation of reference normal for NT-proBNP? Clinical levels for enhanced assessment of NT-proBNP (CLEAN)
March 2011
The natriuretic peptides, B-type natriuretic peptide (BNP) and NT-proBNP that have emerged as tools for diagnosing congestive heart failure (CHF) are affected by age and renal insufficiency (RI). NT-proBNP is used in rejecting CHF and as a marker of risk for patients with acute coronary syndromes. This...
Hypofibronectinaemia in leprosy
March 2011
The aim of this study is to determine the levels of plasma fibronectin in leprosy patients of Nigerian origin. Seventy leprosy patients, 42 men and 28 women, aged 20 to 70 years, of Mile 4 Hospital Abakalilki in Ebonyi State of Nigeria and seventy age and sex-matched apparently normal subjects were used. Some (44) of the patients were on multiple drug therapy with dapsone, rifampicin, and clofazimine as the...
Prevalence of iron deficiency and iron deficiency anemia among females at university stage
January 2011
Iron deficiency is the most prevalent nutritional problem in many parts of the world and the most common cause of anemia in Saudi Arabia especially among female. Accordingly, this study was designed to determine the prevalence of iron deficiency and iron deficiency anemia among apparently healthy Saudi young female university students studying at King Abdulaziz University in Jeddah province. Three hundred ten...
Comparison of matrix-assisted laser desorption ionization-time of flight mass spectrometry (maldi-tof ms) with conventional culture and biochemical method of bacteria identification to species level
January 2011
Identification of bacteria to species level is based on culturing in different media which takes 48 to 72 h from the time of isolation. Matrix-assisted desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) is a new technology in bacteria identification. We evaluated MALDI-TOF-MS system with 101 consecutively isolated bacteria colonies under routine laboratory conditions by comparing its identification...
Selenium levels in patients with schizophrenia
December 2010
The present study was conducted with serum of twenty four patients of schizophrenia and twenty healthy volunteers; and selenium (Se) levels were determined by atomic absorption spectrophotometer. Serum Se levels were significantly increased in schizophrenia patients as compared to healthy controls. Soil content of Se in Rohtak was found to be lower as compared to Haryana state soil Se levels. These findings...
Socio-demographic characteristics of patients presenting pulmonary tuberculosis in a Primary Health Centre, Zaria, Nigeria
December 2010
Tuberculosis is one of the killer diseases of great antiquity especially in developing countries and so contributes significantly to health instability and economic loss. The directly observed treatment(DOT) course is the recommended standard of care in treatment of tuberculosis worldwide and its key elements lie in making the diagnosis. The study was aimed at examining the socio-demographic characteristics of patients...
Glucose-6-phosphate dehydrogenase deficiency in blood donors and jaundiced neonates in Osogbo, Nigeria
April 2010
A study on the prevalence of glucose-6-phosphate dehydrogenase (G6PD) deficiency in blood donors and in jaundiced neonates was carried out. 286 subjects consisting of 200 blood donors and 86 jaundiced neonates were screened for G6PD. Presence of G6PD and bilirubin levels (total and conjugated) were determined in all the subjects. G6PD was determined using two standard methods; methaemoglobin reduction and fluorescent...
In vitro thalidomide does not interfere with the activation of complement by Mycobacterium leprae
April 2010
One inflammatory event that may be involved in erythema nodosum leprosum (ENL) is the activation of complement, and thalidomide could suppress ENL by inhibiting its activation. To determine if thalidomide inhibits the activation of complement, we first incubated normal serum with Mycobacterium leprae or with zymosan in the presence of thalidomide. Residual functional complement was then determined by defining...
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