African Journal of
Cellular Pathology

OFFICIAL PUBLICATION OF THE SOCIETY FOR CELLULAR PATHOLOGY SCIENTISTS OF NIGERIA
  • Abbreviation: Afr. J. Cell. Path
  • Language: English
  • ISSN: 2449-0776
  • DOI: 10.5897/AJCPath
  • Start Year: 2013

AJCPath Articles in press

Article in Press

Effect of Formalin Fixation on DNA purity, Quantity and Amplicon size and Cervical Human Papillomavirus detection in patient attending tertiary health hospitals in Bayelsa State.

Tissue fixation with 10 % formalin and molten paraffin wax embedding (FFPE) is routinely used protocol for tissue preservation in histopathology. DNA fragmentation and possible mutations artifacts which are FFPE processing techniques dependent. They are major setbacks in molecular studies. The decrease in the purity and quantity of nucleic acid recovered from FFPE is a major disadvantage for molecular diagnosis and next...

Author(s):Oboma Yibala I

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