Article in Press
Background: Diabetes mellitus is one of rapidly increasing non communicable disease oblige a continuous medical care, mainly life time patient’s adherence to life style modification recommendations. Poor adherence to lifestyle recommendations leads to poor glycemic control and associated micro and macro-vascular complications; however most patients have difficulty in adhering to the lifestyle modifications including...
Article in Press
Type 2 Diabetes Mellitus (T2DM) is characterized by chronic hyperglycemia and associated with an increased production of reactive oxygen species (ROS) affecting beta cells in pancreas. Glutathione S-transferases (GSTs) are a family of antioxidant enzymes that include several classes of GSTs. These enzymes have important roles in decreasing ROS species and act as a kind of antioxidant defense. In a case-control study we...
Lycopene attenuates diabetes-induced oxidative stress in Wistar rats
Article in Press
The purpose of this study is to evaluate the capacity of lycopene against diabetes-induced oxidative damage in Wistar rats. Thirty Wistar rats of both sexes, twenty-five of which were diabetic, were used. Diabetes was induced by single intraperitoneal injection of streptozotocin (STZ) 60 mg/kg body weight and it was confirmed by the elevated blood glucose ≥200 mg/dl after three days. The rats were divided randomly into...
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