African Journal of
Cellular Pathology

OFFICIAL PUBLICATION OF THE SOCIETY FOR CELLULAR PATHOLOGY SCIENTISTS OF NIGERIA
  • Abbreviation: Afr. J. Cell. Path
  • Language: English
  • ISSN: 2449-0776
  • DOI: 10.5897/AJCPath
  • Start Year: 2013
  • Published Articles: 107

Effect of a cassava based diet (gari) on some renal function parameters in albino rats

Adegoke O.A
  • Adegoke O.A
  • Department of Medical Laboratory Science, Madonna University,Elele, Nigeria
  • Search for this author on:
  • Google Scholar
Bamigbowu E.O
  • Bamigbowu E.O
  • Department of Chemical Pathology, University of Port Harcourt, Port Harcourt, Nigeria
  • Search for this author on:
  • Google Scholar
George–Opuda M. I
  • George–Opuda M. I
  • Department of Medical Laboratory Science, Rivers State University of Science and Technology, Port Harcourt, Nigeria
  • Search for this author on:
  • Google Scholar
Awopeju T A
  • Awopeju T A
  • Department of Medical Microbiology and Parasitology, University of Port Harcourt, Port Harcourt, Nigeria
  • Search for this author on:
  • Google Scholar
Mbata C A
  • Mbata C A
  • Department of Medical Laboratory Science, Rivers State University of Science and Technology, Port Harcourt, Nigeria
  • Search for this author on:
  • Google Scholar
Braide S A
  • Braide S A
  • Institute of Pollution Studies, Rivers State University of Science and Technology, Port Harcourt, Nigeria
  • Search for this author on:
  • Google Scholar
Ekwusa O. V
  • Ekwusa O. V
  • School of Medical Laboratory Science, University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria
  • Search for this author on:
  • Google Scholar
Odunfa T
  • Odunfa T
  • Department of Medical Laboratory Science, Rivers State University of Science and Technology, Port Harcourt, Nigeria
  • Search for this author on:
  • Google Scholar


  •  Received: 01 May 2015
  •  Accepted: 01 June 2015
  •  Published: 30 June 2015

Abstract

Aim: The study was carried out to ascertain the effect of Gari (a cassava based diet) on renal functions in albino rats.

Methods: Thirty five Wistar albino rats divided into seven groups were fed Gari mixed with normal rat diet at concentrations of 0, 10, 20, 40, 60, 80, and 100% respectively for 3 weeks and the renal parameters (Creatinine, Urea, Sodium and Potassium) monitored in the animals.

Results: There were dose dependent increases in urea, creatinine, potassium and sodium of albino rats fed Gari diet. Using analysis of variance (ANOVA), there were significant differences in the urea, and creatinine concentrations when compared to their respective controls (P<0.05) while sodium and potassium did not show any significant difference (P>0.05).

Conclusion: Therefore this study showed that Gari caused changes in renal function based on the concentration of the Gari.

Keywords : Renal, Gari, Creatinine, Urea, Electrolytes

Copyright © 2024 Author(s) retain the copyright of this article.

This article is published under the terms of the Creative Commons Attribution License 4.0

Back to Vol. 4 No. 6
Back to articles
SUBSCRIBE TO RSS
SUBMIT MANUSCRIPT
CONFERENCES