African Journal of
Cellular Pathology

OFFICIAL PUBLICATION OF THE SOCIETY FOR CELLULAR PATHOLOGY SCIENTISTS OF NIGERIA
  • Abbreviation: Afr. J. Cell. Path
  • Language: English
  • ISSN: 2449-0776
  • DOI: 10.5897/AJCPath
  • Start Year: 2013
  • Published Articles: 64

Full Length Research Paper

Histomorphology of seminal vesicle and testicular tissue of Wistar rats following administration of Carica Papaya

Zenebo V. C.
  • Zenebo V. C.
  • Histopathology Section, Medical Laboratory Services, Braithwaite Memorial Specialist Hospital, Port Harcourt, Rivers State Nigeria.
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Eric U. C.
  • Eric U. C.
  • Department of Medical Laboratory Science, Niger Delta University, Wilberforce Island, Bayelsa State, Nigeria
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  •  Received: 01 May 2017
  •  Published: 30 June 2017

Abstract

Aim:  This  study  was  aimed  at  evaluating  the  effect  of  Carica  papaya  on  male
reproductive organs.
Methods: Twenty Wistar rats were randomly grouped into 4 of 5 rats each. They were fed with 2.5g/kg, 5g/kg and 7.5g/kg of ethanolic extract of Carica papaya once a day. The first group was given water. The rats were sacrificed on the 14th day and blood and tissues were taken for biochemical and histological analysis.
Results: There was significant increase (P˂0.05) in  serum  protein  (83.60±3.209, 78.80±1.483 and 72.60±3.578) and alkaline phosphatase (95.80±2.387, 62.80±2.168 and 99.60±1.817) when compared with the controls (64.40±3.286 and 55.60±4.722) respectively. The histology of the tissues was also normal.
Conclusion: Carica papaya leaf at various dosages in this research did not distort blood chemistry and the histo-architecture of the seminal vesicle and testicular tissue.
 
Key Words: Spermatogenic cells, Herbal, Reproduction, Carica papaya.