African Journal of
Cellular Pathology

OFFICIAL PUBLICATION OF THE SOCIETY FOR CELLULAR PATHOLOGY SCIENTISTS OF NIGERIA
  • Abbreviation: Afr. J. Cell. Path
  • Language: English
  • ISSN: 2449-0776
  • DOI: 10.5897/AJCPath
  • Start Year: 2013
  • Published Articles: 64

Serum biochemical changes in Japanese quail (coturnix coturnix japonica) experimentally infected with salmonella enterica serovar gallinarum

Barde I.J
  • Barde I.J
  • Central Diagnostic Laboratory, National Veterinary Research Institute, P.M.B.1.Vom,Plateau State, Nigeria
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Bale J.O.O
  • Bale J.O.O
  • Department of Veterinary Pathology, Ahmadu Bello University, Zaria, Kaduna State, Nigeria
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Oladele S.B
  • Oladele S.B
  • Department of Veterinary Pathology, Ahmadu Bello University, Zaria, Kaduna State, Nigeria
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Fatihu M.Y
  • Fatihu M.Y
  • Department of Veterinary Pathology, Ahmadu Bello University, Zaria, Kaduna State, Nigeria
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Kumbish P.R
  • Kumbish P.R
  • Central Diagnostic Laboratory, National Veterinary Research Institute, P.M.B.1.Vom,Plateau State, Nigeria
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Rimfa A.G
  • Rimfa A.G
  • Central Diagnostic Laboratory, National Veterinary Research Institute, P.M.B.1.Vom,Plateau State, Nigeria
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Ahmed J.S
  • Ahmed J.S
  • Central Diagnostic Laboratory, National Veterinary Research Institute, P.M.B.1.Vom,Plateau State, Nigeria
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Okewole P.A
  • Okewole P.A
  • Central Diagnostic Laboratory, National Veterinary Research Institute, P.M.B.1.Vom,Plateau State, Nigeria
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  •  Received: 01 April 2015
  •  Accepted: 01 May 2015
  •  Published: 31 May 2015

Abstract

Aim: To determine the serum biochemical changes in Japanese quail (Coturnix coturnix japonica) experimentally infected with Salmonella enterica serovar Gallinarum

Methods: A total of 160 (108 males and 52 females) Japanese quails (Coturnix coturnix japonica) were used for the experiment. Four weeks old quails were randomly selected and assigned into four groups (A, B,C and D) of forty quails each. Groups A, B and C were infected with Salmonella enterica serovar Gallinarum per os at the dose of 106,104and102, respectively, while group D served as the control. Sera were used for the determination of biochemical parameters.

Results: There were significant changes (P<0.05) in serum glucose,total protein, albumin, aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP) and urea concentrations between infected groups and the control group.Significant changes (P<0.05) in these biochemical parameters were also observed post-infection compared to pre-infection within each infected group.

Conclusion: FT in quails results in severe multi organ dysfunction and damage as demonstrated by the serum biochemical changes noticed suggestive of immediate cause of mortality in FT infection.

Key words: Serum biochemistry, Quail, Salmonella, Nigeria