Abstract

There is rapidly growing interest in the potential for synergistic, clinically relevant therapeutic responses by combining radiation therapy with immune response. A new mathematical model of radioimmunotherapy for tumor treatment was introduced. In this work, the linear and exponential spatial dependence of tumor parameters was used. The dose distributions model of radiotherapy with immune response for tumor treatment was formulated. A discussion, on the effect of immune response with radiotherapy for the treatment of tumor is explained in details.

Key words: Solid tumor, mathematical model, radioimmunotherapy, immune response.