African Journal of
Medical and Health Sciences

OFFICIAL PUBLICATION OF THE FEDERAL TEACHING HOSPITAL, ABAKALIKI, NIGERIA
  • Abbreviation: Afr. J. Med. Health Sci.
  • Language: English
  • ISSN: 2384-5589
  • DOI: 10.5897/AJMHS
  • Start Year: 2017
  • Published Articles: 59

Full Length Research Paper

Correlation of body mass index (BMI) with hematological indices and procoagulants among people with obesity in Sapele, Southern Nigeria

Kingsley Chukwuka Amaihunwa
  • Kingsley Chukwuka Amaihunwa
  • Department of Medical Laboratory Services, General Hospital Oghara, Delta State, Nigeria.
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Emmanuel Asuquo Etim
  • Emmanuel Asuquo Etim
  • Department of Hematology and Blood Transfusion Science, Federal Medical Center Yola, Adamawa State, Nigeria.
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Everista Odaburhine Osime
  • Everista Odaburhine Osime
  • Department of Medical Laboratory Science, University of Benin, Edo State, Nigeria.
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Zacchaeus Awortu Jeremiah
  • Zacchaeus Awortu Jeremiah
  • Department of Medical Laboratory Science, Rivers State University, Rivers state, Nigeria.
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  •  Received: 27 August 2021
  •  Accepted: 11 October 2021
  •  Published: 31 October 2021

Abstract

Obesity occurs when Body Mass Index (BMI) of an individual is above 30.0 with several effects on hematological indices and procoagulants hence, this study aims to evaluate correlation of BMI with hematological indices and procoagulants among people with obesity. This was a cross sectional and descriptive study carried out at Central Hospital, Sapele, General Hospital, Oghara and Biomed Diagnostic Centre, Sapele in Southern Nigeria. 415 subjects with age between 18 and 65years were enrolled for this study including 312 obese experimental subjects (comprising of 111males and 201females) and 103 non-obese normal control subjects (comprising 40males and 63females). 5.0mls of venous blood was collected from all subjects into EDTA container for Full Blood Count determination using Sysmex XN330 automated hematology analyzer and plasma procoagulant level was determined using ELISA method. Data analysis was done using Microsoft Excel 2010 and Statistical Package for Social Sciences (IBM SPSS) version 21.0 software. The collated results were expressed as mean and standard deviation. BMI had a significant correlation with NLR at P<0.05 while PLR, MPV, PDW and Platocrit had no significant correlation with BMI. Correlation matrix of the relationship between BMI and procoagulant parameters reveals that, BMI had significant correlation with TF, sVCAM, and vWFAg at P<0.05. While, FG, tPA and PAI had no significant correlation with BMI at P<0.05. BMI had significant correlation with NLR, TF, sVCAM, and vWFAg while PLR, MPV, PDW, Platocrit, FG, tPA and PAI had no significant correlation with BMI among people with obesity.

Key words: Body mass index (BMI), hematology indices, procoagulants, Sapele, Nigeria.