August 2017

In vivo and in vitro evaluation of antiplasmodial activity of Amasonia campestris (Aubl.) Moldenke

In this study, phytochemical screening and evaluation were done for the antiplasmodial activity using in vitro test in Plasmodium falciparum and in vivo test in murine model (Plasmodium berghei) of the crude ethanolic extract of roots of Amasonia campestris (Aubl.) Moldenke (CEEAc), popularly known as mendoca and according to surveys ethnobotanically performed in this study, it is used as antimalarial in the State of...

Author(s): Elizabeth Viana Moraes da Costa, Glenda Quaresma Ramos, Larissa Daniele Machado Góes, Cleydson Breno Rodrigues dos Santos, Valter Ferreira de Andrade Neto and José Carlos Tavares Carvalho,

August 2017

Evaluation of the colo-protective effects of tadalafil in an experimental model of ulcerative colitis in rats

Ulcerative colitis is a serious premalignant condition with a confusing multifactorial pathogenesis. It should warrant all attention by researchers, for exploration of new prophylactic or therapeutic drugs targeting its pathophysiology. The current study was conducted to study the possible role of tadalafil and its potential actions in ulcerative colitis rat model, induced by acetic acid. Forty eight male Wistar albino...

Author(s): Dina A. Aly Labib, Walaa Yehia Abdelzaher, Olfat G. Shaker and Lobna O. Elfarouk

August 2017

Ozonation process for hazardous drugs molecules in aqueous media

This study presents results of ozonation of some different aromatic rings of medicines in aqueous solution. The aim of the research was to investigate the influence of ozone on ring cleavage of drug molecules with an aromatic structure. In this regard, phenobarbital, naphazoline, doxycycline, isoniazid and salbutamol were chosen for exposure to ozone gas overnight. It is proved that ozone can attack the OH groups,...

Author(s): Atoosa Haghighizadeh and Omid Rajabi