March 2018

Extract and chloroform fraction from Syzygium cumini leaves with vasorelaxant effect mediated by inhibition of calcium channels

Hypertension is associated with endothelial dysfunction characterized by decreased vasorelaxation. Our research group recently demonstrated that hydroalcoholic extract of Syzygium cumini leaves (HESc) reduces the blood pressure in spontaneously hypertensive rats (SHR). This study evaluated the ability of HESc and chloroform fraction (CF) in promoting vasorelaxation on resistance arteries rings. Endothelium-deprived...

Author(s): Rachel Melo Ribeiro, Matheus Brandão Campos, Ellen Julli da Silva Passos Maia, Gizele Oliveira Santos-Silva, Iracelle Carvalho Abreu, Vicente Ferrer Pinheiro Neto, Marilene Oliveira Rocha Borges and Antonio Carlos Romão Borges