May 2016

In vivo anti-inflammatory and in vitro antioxidant properties of Hilleria latifolia and Laportea ovalifolia

Inflammation which is a normal phenomenon involved in healing of injurious tissue can be complicated with reactive oxygen resulting in chronic inflammatory state and subsequent tissue damage. Since there are reports on severe side effects associated with the use of synthetic anti-inflammatory medications, there is the need to search for new medications with milder side effects. The study, therefore, investigated the...

Author(s): Susana Oteng Dapaah, Christian Agyare, David Darko Obiri, Yaw Duah Boakye and Newman Osafo

May 2016

Studies on gastrointestinal properties of ethanolic leaf extract of Salacia lehmbachii in Wistar rats

Salacia lehmbachii Loes, is used traditionally in Nigeria for the treatment of gastrointestinal disorders. The aim of this study was to investigate the anti-ulcer and anti-diarrhoeal activities of the ethanolic leaf extract of S. lehmbachii. The ethanolic leaf extract was evaluated for castor oil-induced diarrhoeal, intestinal transit as well as intestinal fluid accumulation in rats, while indomethacin, water immersion...

Author(s): Essien, A. D., Essiet Grace A., Akuodor, G. C., Aja, D. O. J., Thomas Edidara E., Nwadike, K. I., Nwachukwu, D. C. and Chilaka, K. C.