African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2184

Table of Content: 8 August, 2018; 12(23)

August 2018

Cross-cultural adaptation and validation to Brazil of the “Medication Counseling Behavior Guidelines”

This work aimed to translate cross-culturally adapts, and validate the “Medication Counseling Behavior Guidelines” instrument into Brazilian Portuguese. The process of cross-cultural adaptation was carried out using international recommendations. The generated versions were evaluated for the semantic, idiomatic, cultural, and conceptual equivalences and the pre-test was carried out with undergraduate...

Author(s): Anne Caroline Oliveira dos Santos, Felipe Pimentel Paixão, Alessandra Rezende Mesquita, Izadora Menezes da Cunha Barros, Kérilin Stancine Santos Rocha, Sabrina Cerqueira Santos, Chiara Ermínia da Rocha, and Divaldo Pereira de Lyra Júnior  

August 2018

Cytotoxic potential of ethanol extract of Parquetina nigrescens on MCF-7, C4-2WT, HT 29 and HTC 116 cell lines

The cytotoxic activity of ethanol extract of Parquetina nigrescen was investigated using a (3-(4, 5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, methylene blue and Trypan Blue exclusion assay on four human cancer cell lines, MCF-7, HT 29, HTC 116 and C4-2WT. A mitochondrial enzyme in living cells, succinate-dehydrogenase cleaves the tetrazolium ring and converts the MTT to an insoluble purple...

Author(s): Blessing M. Onyegeme-Okerenta, Christian Agyare, Tracey D. Bradshaw and Keith A. Spriggs