October 2017

Preparation and evaluation of carbopol coated maize starch: A novel multifunctional excipient

The aim of this study was to enhance the classical adjuvant functionality of maize starch (Mst) by co-processing with small quantities of carbopol 974P (CaPol). A pre-processed maize starch (MpS) was coated with different concentrations of CaPol corresponding to 0.25, 0.5, 0.75 and 1.0 %w/w and spray-dried at controlled conditions to produce the CaPol-coated motifs (MpS-CaPol). The relevant physicochemical and...

Author(s): Philip F. Builders, Chukwuemeka C. Mbah and Boma  B. Mohammed

October 2017

Evaluation of some metabolic activities and immuno-stimulatory potential of methanolic seed extract of Garcinia kola (Heckel) in female albino Wistar rats

Evaluation of some metabolic activities and immuno-stimulatory potential of the methanolic seed extract of Garcinia kola (Heckel) in female albino Wistar rats was carried out using standard methods. Animals in treated groups were administered 125, 250 and 500 mg/kg body weight, respectively of the extract through the oral route for 21 days. The control group received normal saline (0.5 ml/100 g body weight) for the same...

Author(s): B. B. Bukar, D. W. Dayom, O. S. Okpeke, L. Ior, K. D. Falang and M. O. Uguru