December 2007

Efficacy of hibitane® on some nosocomial isolates of S. aureus, E. coli and C. albicans

The effectiveness of the disinfectant hibitane on some microorganisms associated with nosocomial infections were assessed at various use-dilutions of 1: 10, 1: 100, 1: 200 and 1: 2000 constituted using aqueous ethanol and 10% serum solutions. The shapes of the death curves were qualitatively similar for all the organisms exhibiting an initial shoulder (lag), the duration of which depended on hibitane® concentration...

Author(s): El Mahmood, A. M. and Doughari, J. H.

December 2007

Cross-linked nanoparticles of cytarabine: encapsulation, storage and in-vitro release

This work presents results of the preparation and characterization of nanoparticles for entrapping cytarabine, a chemotherapeutic agent. The particle size analysis indicated a uniform particle size. The study of the release of drug from nanoparticles exhibited a prolonged release profile as studied over a period of 16 hours. The drug release was constant from the 10th to the 16th hours, which showed that the formulation...

Author(s): Nisha Mary Joseph and Pramod Kumar Sharma