Biotechnology and Molecular Biology Reviews

  • Abbreviation: Biotechnol. Mol. Biol. Rev.
  • Language: English
  • ISSN: 1538-2273
  • DOI: 10.5897/BMBR
  • Start Year: 2006
  • Published Articles: 103

Review

Cold-active microbial Lipases: a versatile tool for industrial applications

Babu Joseph1*, Pramod W. Ramteke1, George Thomas2, and Nitisha Shrivastava1
1Department of Microbiology and Microbial Technology, College of Biotechnology and Allied Sciences, Allahabad Agricultural Institute- Deemed University, Allahabad 211 007, Uttar Pradesh, India. 2Department of Molecular Biology and Genetic Engineering, College of Biotechnology  and Allied Sciences, Allahabad Agricultural Institute- Deemed University, Allahabad 211 007, Uttar Pradesh, India.
Email: [email protected]

  •  Accepted: 11 May 2007
  •  Published: 30 June 2007

Abstract

Lipases are a class of enzymes which catalyze the hydrolysis of long chain triglycerides and constitute the most important group of biocatalysts for biotechnological applications. Cold active lipases have lately attracted attention as a result of their increasing use in the organic synthesis of chiral intermediates. Due to their low optimum temperature and high activity at very low temperatures, which are favorable properties for the production of relatively frail compounds. Cold active lipases are today the enzymes of choice for organic chemists, pharmacists, biophysicists, biochemical and process engineers, biotechnologists, microbiologists and biochemists. The present review describes various industrial applications of cold active microbial lipases in the medical and pharmaceuticals, fine chemical synthesis, food Industry, domestic and environmental applications.
 
Key words: Biocatalysts, cold active lipase, enzymes, industrial application, lipolytic, Psychrophiles.