Biotechnology and Molecular Biology Reviews

  • Abbreviation: Biotechnol. Mol. Biol. Rev.
  • Language: English
  • ISSN: 1538-2273
  • DOI: 10.5897/BMBR
  • Start Year: 2006
  • Published Articles: 101

Table of Content: April 2008; 3(2)

April 2008

The retinoblastoma binding protein 6 is a potential target for therapeutic drugs

The retinoblastoma binding protein 6 (RBBP6) proteins (also called P-53 Associated Cell Testis Derived (PACT)) are highly upregulated in esophageal cancer and enhance the activity of MDM2, a p53 inhibitor with ubiquitin ligase activity that is over expressed in many human cancers.  Mammalian RBBP6 binds the tumour suppressor proteins p53 and the retinoblastoma protein (Rb). The invertebrate orthologues, on the...

Author(s): Monde Ntwasa

  • Article Number: AFD4FC040222

April 2008

Molecular marker technology in cotton

Molecular markers have been a valuable tool in cotton breeding investigations. Various marker techniques used in cotton include Restriction Fragment Length Polymorphism (RFLP), Random Amplified Polymorphic DNA (RAPD), Amplified Fragment Length Polymorphism (AFLP), Simple Sequence Repeats (SSR), Inter Simple Sequence Repeats (ISSR) and Sequence Related Amplified Polymorphism (SRAP).They have large...

Author(s): Preetha, S and Raveendren T. S 

  • Article Number: 5B6BBF840223

April 2008

Mechanistic links between maternal bacterial infection and cerebral palsy

Maternal bacterial infection is known as a causal factor for preterm labor and neonatal morbidity. In recent years, both epidemiological and experimental studies have identified maternal bacterial infection as one of the causal factors for the development of cerebral palsy (CP) in the offspring. This review examines accumulating evidence that as critical mediators of the host’s response to fighting...

Author(s): Heping Zhou

  • Article Number: DFA47FD40220