April 2010

Kojic acid: Applications and development of fermentation process for production

Kojic acid, 5-hydroxy-2-hydroxymethyl-g-pyrone, has many potential industrial applications. In this review, the properties and diverse applications of kojic acid in industries are described. The review also discusses the advance in kojic acid fermentation, focusing on the process development in micro-organisms and strain selection, medium and culture optimization, as well as fermentation modes for commercially viable...

Author(s): Rosfarizan Mohamad, Mohd Shamzi Mohamed, Nurashikin Suhaili,Madihah Mohd Salleh  and Arbakariya B. Ariff 

April 2010

Transition metal complexes as potential therapeutic agents

Transition metals have important place within medicinal biochemistry. Research has shown significant progress in utilization of transition metal complexes as drugs to treat several human diseases like carcinomas, lymphomas, infection control, anti-inflammatory, diabetes, and neurological disorders. Transition metals exhibit different oxidation states and can interact with number of negatively charged molecules. This...

Author(s): Shazia Rafique, Muhammad Idrees, Anwar Nasim, Haji Akbar and Amin Athar