International Journal of
Medicine and Medical Sciences

  • Abbreviation: Int. J. Med. Med. Sci.
  • Language: English
  • ISSN: 2006-9723
  • DOI: 10.5897/IJMMS
  • Start Year: 2009
  • Published Articles: 518

Full Length Research Paper

A study of the antioxidative potentials of acetone and aqueous extracts of Parkia biglobosa and Tetracarpidium conophorum stem barks in vitro

Olabinri, B. M.
  • Olabinri, B. M.
  • Department of Biochemistry, Ladoke Akintola University of Technology, Ogbomoso, Nigeria.
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Adetutu, A.
  • Adetutu, A.
  • Department of Biochemistry, Ladoke Akintola University of Technology, Ogbomoso, Nigeria.
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Olaleye, M. T.
  • Olaleye, M. T.
  • Department of Biochemistry, Federal University of Technology, Akure, Nigeria.
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Oluwafunsho, B. O.
  • Oluwafunsho, B. O.
  • Department of Biochemistry, Ladoke Akintola University of Technology, Ogbomoso, Nigeria.
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Oyeniyi, O. O.
  • Oyeniyi, O. O.
  • Department of Biochemistry, Ladoke Akintola University of Technology, Ogbomoso, Nigeria.
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  •  Accepted: 26 June 2013
  •  Published: 11 August 2013

Abstract

 

A study of in vitro antioxidative potentials of acetone and aqueous extracts of Parkia biglobosa andTetracarpidium conophorum stem barks were investigated. At all concentrations investigated (50 to 250 µg/ml), the acetone extract of P. biglobosa and T. conophorum stem barks failed to scavenge hydroxyl radical in vitro. Polyphenol extract of T. conophorum stem bark failed to exhibit antioxidant activity in vitro at all concentrations except at 250 µg/ml, where it exhibited weak antioxidant activity (19.6%). P. biglobosa extract showed concentration dependent increase in antioxidant activity with increase extraction time (10 to 30 min). The maximum antioxidant activity of the aqueous stem bark extracts of P. biglobosa and T. conophorum were 87.68% at 50 min and 76.16% at 10 min, respectively.

 

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