International Journal of
Medicine and Medical Sciences

  • Abbreviation: Int. J. Med. Med. Sci.
  • Language: English
  • ISSN: 2006-9723
  • DOI: 10.5897/IJMMS
  • Start Year: 2009
  • Published Articles: 535

Full Length Research Paper

Prevalence and antibiotic susceptibility of uropathogens among patients attending University of Abuja Teaching Hospital, Gwagwalada, Abuja

N. J. Amaeze, A.U. Abah and I. N. Okoliegbe
Department of Biological Sciences, University of Abuja, Abuja, Nigeria.
Email: [email protected]

  •  Accepted: 28 August 2013
  •  Published: 30 October 2013

Abstract

 

A urinary tract infection (UTI) is a condition where one or more structures in the urinary tract become infected by the presence and growth of microorganisms that overcome the structures strong natural defenses. This study reports the examination of bacterial organisms implicated in urinary tract infections among 180 patients suspected to have UTI that attended University of Abuja Teaching Hospital (UATH), Gwagwalada, Abuja for a period of 3 months and the antibiotic susceptibility patterns of the bacterial isolates. First morning mid stream urine sample cultures were done by the calibrated loop technique delivering 0.002 ml of urine plated on Cystine Lactose Electrolyte Deficient (CLED) agar and blood agar medium for isolation of uropathogens which were further analyzed for drug susceptibility by disk diffusion method. Result showed that 104 (57.78%) patients had urinary tract infection. The uropathogens isolated were Escherichia coli as the most abundant (43.27%) followed by Staphylococcus aureus (35.57%), Klebsiella species (11.54%), Proteus species (5.77%) and Pseudomonas species (3.85%) as the least occurring. Invitro antibiotic susceptibility test revealed that the Gram negative bacteria were most sensitive to quinolones (ofloxacin and levofloxacin), gentamycin and nalixidic acid while the Gram positive isolates were sensitive to erythromycin, chloramphenicol and quinolones (ofloxacin and levofloxacin). The most effective drug in both cases was the quinolones–ofloxacin (78.32%) and levofloxacin (76.98%), while the least sensitivity pattern was observed with ampicillin (14.29%).

 

Key words: Urinary tract, uropathogens, antibiotics susceptibility.