International Journal of
Medicine and Medical Sciences

  • Abbreviation: Int. J. Med. Med. Sci.
  • Language: English
  • ISSN: 2006-9723
  • DOI: 10.5897/IJMMS
  • Start Year: 2009
  • Published Articles: 513

Effect of maternal iron status on placenta, fetus and newborn

K. N. Agarwal
  • K. N. Agarwal
  • Indian National Science Academy & Present health Care & Research Association, D-115, Sector -36, NOIDA, Gautam Budha Nagar-201301, India.
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V. Gupta
  • V. Gupta
  • Anderson Cancer Center, Houstan Tx, USA.
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S. Agarwal
  • S. Agarwal
  • Reader Pediatrics Institute Medical Sciences, Varanasi, India.
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  •  Accepted: 19 June 2013
  •  Published: 11 September 2013



Maternal anemia (hypoferriemia) results in increased pre-term and low birth weight deliveries and higher rate of stillbirths. There are irreversible structural alterations in placenta. The transfer of iron to fetus is reduced in spite of gradient in relation to severity of maternal hypoferriemia. The fetal hepatic and brain iron contents were reduced. The brain iron reduction was irreversible on rehabilitation and was associated with irreversible neurotransmitter and their receptor alterations.


Key words: Maternal anemia, stillbirths, placenta.