International Journal of
Medicine and Medical Sciences

  • Abbreviation: Int. J. Med. Med. Sci.
  • Language: English
  • ISSN: 2006-9723
  • DOI: 10.5897/IJMMS
  • Start Year: 2009
  • Published Articles: 510

Full Length Research Paper

Effect of chronic administration of Aloe vera extract on plasma biochemistry in rabbits

Amjad Ali Channa*
  • Amjad Ali Channa*
  • Faculty of Animal Husbandry and Veterinary Sciences, Sindh Agriculture University Tandojam. Pakistan.
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Saeed Ahmed Soomro
  • Saeed Ahmed Soomro
  • Department of Veterinary Physiology and Biochemistry, Faculty of Animal Husbandry animal Veterinary Sciences, Sindh Agriculture University Tandojam. Pakistan.
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Roshan Ali Korejo
  • Roshan Ali Korejo
  • Faculty of Animal Husbandry and Veterinary Sciences, Sindh Agriculture University Tandojam. Pakistan.
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Band-e-Ali Khaskeli
  • Band-e-Ali Khaskeli
  • Faculty of Animal Husbandry and Veterinary Sciences, Sindh Agriculture University Tandojam. Pakistan.
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Tofique Ahmed Qureshi
  • Tofique Ahmed Qureshi
  • Department of Pharmacology, Faculty of Animal Husbandry and Veterinary Sciences, Sindh Agriculture University Tandojam, Pakistan.
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Imtiaz Ahmed Shah
  • Imtiaz Ahmed Shah
  • Faculty of Animal Husbandry and Veterinary Sciences, Sindh Agriculture University Tandojam. Pakistan.
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Nawab Ali Kalhoro
  • Nawab Ali Kalhoro
  • Faculty of Animal Husbandry and Veterinary Sciences, Sindh Agriculture University Tandojam. Pakistan.
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Hinesh Kumar Maheshwari
  • Hinesh Kumar Maheshwari
  • Faculty of Animal Husbandry and Veterinary Sciences, Sindh Agriculture University Tandojam. Pakistan.
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  •  Received: 02 June 2014
  •  Accepted: 24 June 2014
  •  Published: 31 August 2014

Abstract

Due to excessive use, synthetic medicines are going to be expensive and resistant, their residues accumulate in blood, that is why slowly and gradually they become resistant. Alternatives to synthetic medicines are herbal medicines that are cheap, with minimum or no side effect. Previous studies found that liquid extract of Aloe vera plant proved beneficial for animal’s health as it has immune-modulating, hypolipidemic, hypoglycemic and haematinic effects. The aim of this study was to investigate the effect of A. vera extract on plasma biochemistry. A total of twenty (n = 20) male rabbits were selected and divided into 4 groups; P, Q, R and S with five (n = 5) in each group. The group P was kept as control while group Q, R and S were given oral A. vera extract at the dose of 200, 300 and 400 mg/kg body weight, respectively daily for 21 days. Blood samples were taken on various days; 0, 7, 14 and 21 of treatment. Research has found that A. vera significantly (p < 0.05) decrease cholesterol level, that is indication that A. vera has influence on adipose tissues.

 

Key words: Aloe vera, haematology, plasma biochemistry.