Abstract

Toxoplasmosis  is  an  anthropozoonosis  of  medical  and  veterinary  importance,  due  to  the protozoan Toxoplasma gondii. Oocysts shed by felids play a key role in parasite transmission as they contaminate meat-producing animals, vegetables and water consumed later by humans. This study tried to study the effectiveness of spiramycin in the treatment of toxoplasmosis in the laboratory of the Abass NDAO Hospital’s (CHAN) in human immunodeficiency virus (HIV)-positive women (82 cases) using the enzyme immunoassay method solid phase (EIA). It reveals a negativity of IgM antibodies and progressive regression of IgG antibodies more visible in three women as high (between 50 and 100 International Units (IU)/ml) and in three other unreliable in the first immunoglobin M (IgM) serology by a seroconversion at the second serology with a stabilization of immunoglobin (IgG) 10 IU/ml. The effectiveness of current treatment has been demonstrated by low return rate IgG antibodies to 10 IU/ml in those who received 3 million IU of Rovamycin at a dose of 2 tablets for day to one month. These first results need to be followed by more extensive investigations.

Key words: Prevalence, treatment, toxoplasmosis, Toxoplasma gondii.