International Journal of
Physical Sciences

  • Abbreviation: Int. J. Phys. Sci.
  • Language: English
  • ISSN: 1992-1950
  • DOI: 10.5897/IJPS
  • Start Year: 2006
  • Published Articles: 2572

Full Length Research Paper

Ultrasound-assisted extraction flavonoids from Lotus (Nelumbo nuficera Gaertn) leaf and evaluation of its anti-fatigue activity

Lan Zhang1*, Ying Shan2, Keji Tang3 and Ramesh Putheti4
1Zhejiang Yuexiu University of Foreign Languages, Shaoxing, Zhejiang Province, 312000, People’s Republic of China. 2Zhejian University of Technology, Hangzhou, Zhejiang Province, 310014, People’s Republic of China. 3Dezhou University, Dezhou, Shandong Province, 253023, People’s Republic of China. 4American Association of Pharmaceutical Scientists (AAPS), 236-203, Saint David Court, Maryland, USA.
Email: [email protected]

  •  Accepted: 06 July 2009
  •  Published: 31 August 2009

Abstract

In this study, flavonoids were obtained from Lotus (Nelumbo nuficera Gaertn) leaf using ultrasound-assisted extraction method (UAE). Optimum extraction conditions of flavonoids from Lotus leaf (FLL) were investigated through single factor test and orthogonal test. Its anti-fatigue activity was evaluated by swimming test. The results showed that the optimal extraction parameters were as followings: concentration of ethanol solution was 70% , ratio of solvent to raw material was 35, ultrasound time was 25 min. Swimming test results suggested that FLL had significant anti-fatigue activity.

 

Key words: Ultrasound-assisted extraction, Lotus leaf, anti-fatigue activity.

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