International Journal of
Physical Sciences

  • Abbreviation: Int. J. Phys. Sci.
  • Language: English
  • ISSN: 1992-1950
  • DOI: 10.5897/IJPS
  • Start Year: 2006
  • Published Articles: 2572

Full Length Research Paper

Structural elucidation of a new furoclerodane from stem barks of Croton mayumbensis J. Leonard extracts

Sosthène C. Yamale1, Jean Koudou2*, Abdoulaye Samb1, Annie Heitz3 and Jean-Claude Teulade4
1Laboratoire de chimie et biochimie des produits naturels, Faculté des Sciences et Techniques, UCAD, BP7021 Dakar, Sénégal. 2Laboratoire de chimie des substances naturelles, Faculté des Sciences, Université de Bangui, BP908, Bangui, République Centrafricaine. 3CCIPE, rue de la Cardonille, F-34094 Montpellier, France. 4Laboratoire de chimie organique UMR INSERM 484, Faculté de Pharmacie, Université d’Auvergne, France.
Email: [email protected]

  •  Accepted: 12 February 2009
  •  Published: 31 March 2009

Abstract

The stem barks of Croton mayumbensis are used by the healers of Centrafrican Republic against many diseases as microbial infections and amoebiasis. The analysis of different extracts by column chromatography, HPLC coupled with mass spectrometry lead to the identification of a new diterpenoïd with a furoclerodane squeleton. Its structure has been elucidated from spectral data: mass spectrometry, 1H NMR, 13C NMR COSY and NOESY.

 

Key words: Croton mayumbensis, euphorbiaceae, stem barks, furoclerodane,Centrafricine I.

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This article is published under the terms of the Creative Commons Attribution License 4.0

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