In the current study, we examined the effect of Morinda officinalis polysaccharides (MOP) on bone quality in aged rats. Rats were given orally by daily gavage at 200 and 400 mg/kg/day for 3 months, respectively. The results showed that there was a significant decrease in serum alkaline phosphatase (ALP), Interleukin 6 (IL-6) content and a significant increase in density and strength of femur and lumbar vertebrae in aged rats 3 months afterMorinda officinalis polysaccharides treatment. In conclusion, these data suggest thatMorinda officinalis polysaccharides can protect the age-induced bone degeneration.
Key words: Morinda officinalis polysaccharides, bone, osteoporosis, ALP.
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