International Journal of
Physical Sciences

  • Abbreviation: Int. J. Phys. Sci.
  • Language: English
  • ISSN: 1992-1950
  • DOI: 10.5897/IJPS
  • Start Year: 2006
  • Published Articles: 2568

Full Length Research Paper

Beneficial effect of curcumin isolated from Curcuma longa on exercise-induced hepatocyte apoptosis of rat

Fu Jiliang1*, Huang Yongliang1, Chen Hongyu2, Wang Yugui1, Yu Li1, Chu Wenya1 and Ou Xiuling3
1Zhejiang Ocean University, Zhoushan City, Zhejiang Province, 316000, China. 2Zhejiang University, Hangzhou City, Zhoushan City, Zhejiang Province, 310058, China. 3Tianjin Agricultural University, Tianjin City, 300384, China.
Email: [email protected]

  •  Accepted: 29 June 2010
  •  Published: 31 July 2010

Abstract

The aim of this study was to determine the effect of curcumin isolated fromCurcuma longa on exercise-induced hepatocyte apoptosis. 24 male Wistar rats were used for the study. The experiment was a 14-day exhaustive exercise. We determined the protein expression of bax and bcl-2 in the hepatic tissues. The results demonstrated that bax and bcl-2 co-regulated the exercise-induced hepatocyte apoptosis. Bax promotes the apoptosis as up-regulated genes, while bcl-2 inhibits apoptosis as down-regulated genes. Curcumin can inhibit exercise-induced hepatocyte apoptosis. The experimental results provided theoretical support for curcumin in the field of sports nutrition.

 

Key words: curcumin, exercise, apoptosis.

Copyright © 2024 Author(s) retain the copyright of this article.

This article is published under the terms of the Creative Commons Attribution License 4.0

Back to Vol. 5 No. 7
Back to articles
  • Articles on Google by:
SUBSCRIBE TO RSS
SUBMIT MANUSCRIPT
CONFERENCES