February 2010

Sputum cellularity in pulmonary tuberculosis: A comparative study between HIV-positive and -negative individuals

To compare sputum cellularity between HIV-positive and -negative individuals with pulmonary tuberculosis.  A cross-sectional study was conducted in patients with pulmonary tuberculosis. Sputum samples were collected and processed within two hours after collection. The absolute number of squamous cells of a total of 400 cells was counted, as well as the absolute number (× 106 cells/ml) and percentage...

Author(s): Rosemeri Maurici da Silva, Paula Stocco, Maria Luiza Bazzo and Mariana Chagas

February 2010

Comparative tolerability and efficacy of stavudine 30 mg versus stavudine 40 mg in patients on combination antiretroviral therapy in Kenya

Stavudine- containing regimens are currently the most widely used first-line anti-HIV treatment option in Kenya. This study compared the efficacy and tolerability of stavudine at two dose levels in patients attending a HIV Comprehensive Care Centre in Kenya. Data were collected retrospectively from the records of 810 adult patients. Fewer stavudine related adverse effects were seen in patients ≥ 60 kg treated with 30...

Author(s): Monicah Wanjiru Karara, Faith Apolot Okalebo, Margaret Ng’wono Oluka, James Ombega, Anastasia Nkatha Guantai and George Oyamo Osanjo