August 2020

Viral suppression and predictors among adolescents receiving care for HIV/AIDS in a tertiary health centre in Uyo, South-South, Nigeria

Viral suppression assesses the success of HIV/AIDS treatment and can avert or reduce transmission of infection. Several factors contribute to viral suppression and may vary in different settings and age groups, hence the need to study the associated factors in different populations. The aim of the research was to study the level of viral suppression and its predictors among adolescents living with HIV (ALHIV), who knew...

Author(s): Dixon-Umo Ofonime Tony and Ikpeme Enobong Emmanuel    

August 2020

Assessment of the effect of anti-retroviral therapy on haematological parameters in HIV positive individuals in Zaria

A total of 230 patients receiving HAART for the first time and followed regularly were retained and their information gotten using a questionnaire. Of this number, 146 (63.5%) were on Stavudine + Lamivudine + Nevirapine (Regimen 1). 84(36.5%) while the remaining were on zidovudine + Lamivudine + Nevirapine (Regimen 5). The distribution was 75(32.6%) males and 155(67.4%) females. Blood was collected from each patient and...

Author(s): E. M. Kayode, D. O. Usiegbodi, M. E Ajiboye, I. S.Omonye, M. N. Febut and A. S. Buru  

October 2020

Determinants of antiretroviral therapy adherence among older adolescents living with HIV in Kenya during the transition to adult care: An observational study

Lower levels of adherence to antiretroviral therapy (ART) among older adolescents as compared to adults are influenced by individual, psychosocial, and treatment-related factors. Successful transition of older adolescents into HIV adult care from paediatric & adolescent focused care requires an understanding of barriers to ART adherence. This study aimed at determining individual factors affecting ART adherence...

Author(s): Nyawira Gitahi, Samuel Wahome, Maricianah Onono, Elizabeth A. Bukusi, and Kenneth Ngure  

October 2020

Assessment of renal dysfunction and associated factors among patients on Tenofovir based antiretroviral treatment at Gondar University Hospital, North West Ethiopia: Retrospective institution based cross sectional study

Tenofovir Disoproxil Fumarate a nucleotide reverse transcriptase inhibitor that was introduced as a preferred first line antiretroviral therapy in Ethiopia as of 2008. However, routine renal function assessment is recommended as it is known to cause renal failure and renal tubular dysfunction. To assess the practice of renal function monitoring of patients on TDF based ART regimen. The magnitude of renal dysfunction...

Author(s): Endris Ahmed, Ermias Diro, Workagegnehu Hailu and Oumer Abdu Muhie  

November 2020

Treatment outcomes of tenofovir versus zidovudine-based first-line antiretroviral therapy regimens at Zewditu Memorial Hospital: A retrospective cohort study

Tenofovir-based regimen is the preferred first line treatment in Ethiopia despite limited local data on its effectiveness and tolerability over zidovudine-based regimen. Therefore, this study compared the outcomes of tenofovir and zidovudine-based regimens focusing on toxicity driven regimen substitution and mortality. A retrospective cohort study was conducted in Zewditu Memorial Hospital. All ART naïve patients...

Author(s): Abel Terefe, Mamo Feyissa and Workineh Shibeshi