The struggle against the agricultural devastating is increased in few last years and many products are created to kill the harmful insects and bug, without controlling their effect on ecosystem and non-target animals. In present work, we try to investigate the effects of the Flufenoxuron, which is an Insect growth Regulator (IGR) on embryonic development of hen’s eggs as a non-target organism for this pesticide. The pesticide is tested in ovo by injection in the egg air cell of three concentrations in strictly controlled conditions, to show the impact on some biochemical parameters. The treatment with 1, 10 and 20 µg/egg of the pesticide induced some blood parameters perturbations, especially in 10 and 20 µg according to the controls. The 20µg concentration induces the blood serum proteins decreasing, increasing of triglycerides, decreasing of cholesterol and decreasing of Alanine amino transferase (GPT). This concentration induced a great level of embryonic mortality. The 1 and 10µg concentrations perturb (increase/decrease these parameters).

Keywords: Flufenoxuron, IGR, POPs, Gallus domesticus, embryonic development, Triglycerides, GPT, toxicity, cholesterol.