Journal of
Cancer Research and Experimental Oncology

  • Abbreviation: J. Cancer Res. Exp. Oncol.
  • Language: English
  • ISSN: 2141-2243
  • DOI: 10.5897/JCREO
  • Start Year: 2009
  • Published Articles: 53

Short Communication

Long term remission with 6-Mercaptopurine in refractory Evan’s syndrome

I. Tazi
  • I. Tazi
  • Hematology Department, Chu Mohamed VI, University Cadi Ayyad, Marrakech, Morocco.
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H. Nafil
  • H. Nafil
  • Hematology Department, Chu Mohamed VI, University Cadi Ayyad, Marrakech, Morocco.
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L. Mahmal
  • L. Mahmal
  • Hematology Department, Chu Mohamed VI, University Cadi Ayyad, Marrakech, Morocco.
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  • Article Number - 0B114013971
  • Vol.3(2), pp. 20-21, February 2011
  •  Accepted: 25 January 2011
  •  Published: 28 February 2011

Abstract

The management of Evan’s syndrome remains a challenge and innovative approaches are needed. Initial therapeutic failure, relapses after initial response and refractoriness to treatments are typical. Options for second-line therapy include immunosuppressive drugs, especially cyclosporin or mycophenolate mofetil; vincristine; danazol or a combination of these agents. We report here a long-term remission of Evan’s syndrome obtained with 6-mercaptopurine in a 35-year-old female patient.

 

Key words: 6-Mercaptopurine, Evan’s syndrome, remission.