Journal of
Cancer Research and Experimental Oncology

  • Abbreviation: J. Cancer Res. Exp. Oncol.
  • Language: English
  • ISSN: 2141-2243
  • DOI: 10.5897/JCREO
  • Start Year: 2009
  • Published Articles: 53

Case Report

Cerebral leptomeningeal metastasis in a case of primary ovarian lymphoma

Nejmi Kiymaz
  • Nejmi Kiymaz
  • Department of Neurosurgery, University of Yuzuncu Yil, School of Medicine, Van, Turkey.
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Nebi Yilmaz
  • Nebi Yilmaz
  • Department of Neurosurgery, University of Yuzuncu Yil, School of Medicine, Van, Turkey.
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Mustafa Kösem
  • Mustafa Kösem
  • Department of Pathology, University of Yuzuncu Yil, School of Medicine, Van, Turkey.
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Taner Yazici
  • Taner Yazici
  • Department of Neurosurgery, University of Yuzuncu Yil, School of Medicine, Van, Turkey.
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Suleyman Alici
  • Suleyman Alici
  • Department of Medical Onkology, University of Yuzuncu Yil, School of Medicine, Van, Turkey.
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Abdulbaki Kozan
  • Abdulbaki Kozan
  • Department of Neurosurgery, University of Yuzuncu Yil, School of Medicine, Van, Turkey.
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  • Article Number - 72E3F5F3441
  • Vol.2(2), pp. 19-22, April 2010
  •  Accepted: 13 January 2010
  •  Published: 30 April 2010

Abstract

A 38 years old female patient is presented who applied to our neurosurgery clinic due to symptoms such as headache, ataxia, vertigo, vomiting and complaints related to a mass at the back side of her head. The examination of cranial magnetic resonance imaging (MRI) of the patient displayed a mass which obliterates the transverse sinus and extends from the scalp to the epidural space at a certain distance and to the occipital zone. The result of the biopsy report revealed an infiltration of malign lymphoma. The patient received cyclophosphamide, adriablastine, vincristine and prednisolone for 1 - 5 days, at 21 days interval and as 6 cures. A complete response was obtained at the end of the 3 rd cure. The patient was orientated for radiotherapy at the end of the sixth cure. This case is a rarely seen ovarian lymphoma and constitutes a sample for cerebral leptomeningeal metastasis which is a very rare condition.   

 

Key words: Cerebral leptomeningeal metastasis, primary ovarian lymphoma.